How Mounjaro Controls Appetite and Cravings

How Mounjaro Reduces Appetite

Mounjaro (tirzepatide) works by activating two key hormone receptors: GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide). These receptors are found in areas of the brain that control appetite, satiety, and food reward.

When Mounjaro activates these receptors, it sends signals that:

• Reduce hunger signals from the hypothalamus
• Increase feelings of fullness (satiety) after eating
• Decrease the reward value of high-calorie foods
• Slow gastric emptying, keeping you feeling satisfied longer

This dual-action mechanism makes Mounjaro more effective at appetite control than medications that only target one receptor, such as Wegovy.

Controlling Food Cravings

Food cravings, particularly for high-calorie, processed foods, are driven by the brain's reward system. Mounjaro helps control cravings by:

• Reducing Reward Sensitivity: Makes high-calorie foods less appealing
• Stabilising Blood Sugar: Prevents blood sugar crashes that trigger cravings
• Improving Satiety: When you feel full, cravings naturally decrease
• Regulating Hormones: Balances hormones that influence food-seeking behaviour

Many patients report that cravings for sweets, processed foods, and large portions diminish significantly within the first few weeks of treatment.

Timeline of Appetite Reduction

The appetite-reducing effects of Mounjaro typically follow this timeline:

• 24-48 Hours: Initial appetite reduction may be noticeable
• Week 1-2: More consistent appetite suppression as medication builds up
• Week 4-8: Optimal appetite control as dosage increases
• Ongoing: Sustained appetite reduction with regular dosing

Individual responses vary. Some patients notice effects immediately, while others may need dosage adjustments. Our pharmacist monitors your progress and adjusts treatment as needed.

Combining Medication with Lifestyle Changes

While Mounjaro significantly reduces appetite, combining it with healthy lifestyle changes maximises results:

• Nutrition Coaching: Learn to make healthy food choices when appetite is reduced
• Portion Control: Use reduced appetite to establish healthy portion sizes
• Meal Timing: Structure meals to maintain energy and prevent overeating when medication wears off
• Hydration: Stay hydrated, as reduced appetite can sometimes mask thirst

Our Glasgow Weight Loss clinic provides comprehensive support, including nutrition guidance tailored to how Mounjaro affects your appetite. Learn more about our treatment approach.

Mounjaro vs Other Appetite Suppressants

Mounjaro's dual-receptor action provides superior appetite control compared to single-receptor medications:

• More Effective: Dual action targets multiple appetite pathways
• Faster Onset: Many patients notice effects sooner
• Sustained Control: Appetite reduction continues throughout treatment
• Better Cravings Control: Particularly effective at reducing high-calorie food cravings

Compare Mounjaro with Wegovy or see our treatment comparison guide.